Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 16/20 | 0.63 |
| ▸ | CPT2 | P23786 | 11/20 | 0.63 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17801091 | 0.84 | CPT1A (0.60) | CPT1ACPT2CPT1BHCRTR1HCRTR2 | |
| SCHEMBL17801081 | 0.84 | CPT1A (0.46) | CPT1ACPT2CPT1BHCRTR1HCRTR2 | |
| SCHEMBL17801057 | 0.81 | CPT1A (0.51) | CPT1ACPT2CPT1BHCRTR1HCRTR2 | |
| SCHEMBL17801049 | 0.79 | CPT1A (0.52) | CPT1ACPT2CPT1BHCRTR1HCRTR2 | |
| SCHEMBL17801046 | 0.79 | CPT1A (0.45) | CPT1ACPT2CPT1BHCRTR1HCRTR2 | |
| SCHEMBL3551630 | 0.77 | CPT1A (1.00) | CPT1ACPT2CPT1B | |
| SCHEMBL3551631 | 0.77 | CPT1A (1.00) | CPT1ACPT2CPT1B | |
| SCHEMBL17801010 | 0.75 | HCRTR2 (0.44) | CPT1ACPT2CPT1BHCRTR1HCRTR2 | |
| SCHEMBL17801054 | 0.75 | CPT1A (0.55) | CPT1ACPT2CPT1BHCRTR1HCRTR2 | |
| SCHEMBL5377458 | 0.71 | CSNK1D (0.55) | CSNK1DAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016089977-A1 | SUBSTITUTED INDAZOLE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | CELGENE CORPORATION (US) | 2016-06-09 | — | — | WO | disclosed |