Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | IDH2 | P48735 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17801724 | 0.78 | NPC1 (0.44) | MAPTNPC1RAB9APIK3CAPIK3CG | |
| SCHEMBL17812976 | 0.76 | NPC1 (0.42) | MAPTNPC1RAB9APIK3CAPIK3CG | |
| SCHEMBL17317881 | 0.73 | MAPT (0.38) | MAPTPOLBLMNAALDH1A1IDH2 | |
| SCHEMBL17801767 | 0.72 | NPC1 (0.53) | MAPTNPC1RAB9APOLBPIK3CA | |
| SCHEMBL17801753 | 0.71 | NPC1 (0.42) | MAPTNPC1RAB9APIK3CAPIK3CG | |
| SCHEMBL17801728 | 0.70 | SMN1; SMN2 (0.49) | MAPTNPC1RAB9APIK3CAPIK3CG | |
| SCHEMBL17317980 | 0.70 | MAPT (0.37) | MAPTPOLBLMNAALDH1A1IDH2 | |
| SCHEMBL17801780 | 0.70 | NPC1 (0.41) | MAPTNPC1RAB9APIK3CAPIK3CG | |
| SCHEMBL17317943 | 0.69 | MAPT (0.37) | MAPTPOLBLMNAALDH1A1IDH2 | |
| SCHEMBL17801754 | 0.68 | NPC1 (0.59) | MAPTNPC1RAB9APOLBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227283-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016087371-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | WO | disclosed |