Sucrose

SCHEMBL17801786

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nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1 MMP13 MMP7 MMP8 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Sucrose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	CDK1	P06493	1/20	0.64

▸	CCNB1	P14635	1/20	0.64

▸	CA2	P00918	1/20	0.45

▸	CA9	Q16790	1/20	0.45

▸	MEN1	O00255	1/20	0.40

▸	KMT2A	Q03164	1/20	0.40

▸	LDHA	P00338	1/20	0.40

▸	ADORA1	P30542	1/20	0.39

▸	EPHX2	P34913	2/20	0.38

▸	L3MBTL1	Q9Y468	1/20	0.35

▸	TYR	P14679	1/20	0.34

▸	MAPT	P10636	1/20	0.34

▸	POLB	P06746	1/20	0.34

▸	SLC5A2	P31639	3/20	0.34

▸	SLC28A3	Q9HAS3	1/20	0.34

▸	SLC5A1	P13866	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Sucrose SCHEMBL17801785	0.97	CDK1 (0.60)	CDK1CCNB1CA2CA9MEN1
Sucrose SCHEMBL8718558	0.96	CDK1 (0.68)	CDK1CCNB1CA2CA9MEN1
Sucrose SCHEMBL301783	0.96	CDK1 (0.68)	CDK1CCNB1CA2CA9MEN1
Sucrose SCHEMBL10910573	0.96	CDK1 (0.68)	CDK1CCNB1CA2CA9MEN1
Sucrose SCHEMBL350353	0.96	CDK1 (0.68)	CDK1CCNB1CA2CA9MEN1
Sucrose SCHEMBL8323806	0.95	CDK1 (0.67)	CDK1CCNB1CA2CA9MEN1
Sucrose SCHEMBL14152612	0.94	CDK1 (0.60)	CDK1CCNB1CA2CA9MEN1
Sucrose SCHEMBL11039870	0.94	CDK1 (0.68)	CDK1CCNB1CA2CA9MEN1
Sucrose SCHEMBL23886158	0.93	CDK1 (0.64)	CDK1CCNB1CA2CA9MEN1
Sucrose SCHEMBL8922550	0.92	CDK1 (0.68)	CDK1CCNB1CA2CA9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3226894-A1	STABLE LIQUID VACCINIA VIRUS FORMULATIONS	Transgene SA (FR)	2017-10-11	—	—	EP	disclosed
WO-2016087457-A1	STABLE LIQUID VACCINIA VIRUS FORMULATIONS	TRANSGENE SA (FR)	2016-06-09	—	—	WO	disclosed