Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17801966 | 0.89 | ACKR3 (0.56) | ACKR3 | |
| SCHEMBL19582246 | 0.81 | ACKR3 (0.60) | ACKR3 | |
| SCHEMBL17801974 | 0.81 | ACKR3 (0.57) | ACKR3 | |
| SCHEMBL17802006 | 0.77 | ACKR3 (0.62) | ACKR3 | |
| SCHEMBL19582245 | 0.76 | ACKR3 (0.53) | ACKR3 | |
| SCHEMBL17801896 | 0.75 | ACKR3 (0.57) | ACKR3 | |
| SCHEMBL20873632 | 0.74 | ACKR3 (0.39) | ACKR3 | |
| SCHEMBL17801875 | 0.73 | ACKR3 (0.47) | ACKR3 | |
| SCHEMBL19582435 | 0.72 | ACKR3 (1.00) | ACKR3 | |
| SCHEMBL19582231 | 0.72 | ACKR3 (1.00) | ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227263-A1 | CXCR7 RECEPTOR MODULATORS | Actelion Pharmaceuticals Ltd (CH) | 2017-10-11 | — | — | EP | claimed |
| WO-2016087370-A1 | CXCR7 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2016-06-09 | — | — | WO | claimed |
| EP-3227263-A1 | CXCR7 RECEPTOR MODULATORS | Actelion Pharmaceuticals Ltd (CH) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016087370-A1 | CXCR7 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2016-06-09 | — | — | WO | disclosed |