Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.34 |
| ▸ | KDM5C | P41229 | 2/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2720582 | 0.98 | MEN1 (0.39) | MEN1KMT2AKDM4AKDM4CSMN1; SMN2 | |
| SCHEMBL26900583 | 0.98 | MEN1 (0.39) | MEN1KMT2AKDM4AKDM4CSMN1; SMN2 | |
| SCHEMBL12092144 | 0.98 | MEN1 (0.39) | MEN1KMT2AKDM4AKDM4CSMN1; SMN2 | |
| SCHEMBL25413833 | 0.98 | MEN1 (0.39) | MEN1KMT2AKDM4AKDM4CSMN1; SMN2 | |
| SCHEMBL13213153 | 0.98 | MEN1 (0.39) | MEN1KMT2AKDM4AKDM4CSMN1; SMN2 | |
| SCHEMBL24513773 | 0.98 | MEN1 (0.39) | MEN1KMT2AKDM4AKDM4CSMN1; SMN2 | |
| SCHEMBL932529 | 0.98 | MEN1 (0.39) | MEN1KMT2AKDM4AKDM4CSMN1; SMN2 | |
| SCHEMBL23289657 | 0.98 | MEN1 (0.39) | MEN1KMT2AKDM4AKDM4CSMN1; SMN2 | |
| SCHEMBL16132772 | 0.96 | KDM4A (0.38) | MEN1KMT2AKDM4AKDM4CSMN1; SMN2 | |
| SCHEMBL26383116 | 0.87 | BLM (0.48) | MEN1KMT2AKDM4AKDM4CSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903826-B1 | BIOMOLECULE CONJUGATES | CELGENE CORP (US) | 2024-05-08 | — | — | EP | disclosed |
| EP-4289483-A2 | BIOMOLECULE CONJUGATES | Celgene Corporation (US) | 2023-12-13 | — | — | EP | disclosed |
| CN-114656483-A | Biomolecular conjugates | 细胞基因公司 | 2022-06-24 | — | — | CN | disclosed |
| EP-3903826-A1 | BIOMOLECULE CONJUGATES | Celgene Corporation (US) | 2021-11-03 | — | — | EP | disclosed |
| US-10335495-B2 | Biomolecule conjugates | CELGENE CORPORATION (US) | 2019-07-02 | — | — | US | disclosed |
| US-20170360952-A1 | BIOMOLECULE CONJUGATES | CELGENE CORPORATION | 2017-12-21 | — | — | US | disclosed |
| EP-3226910-A1 | BIOMOLECULE CONJUGATES | Celgene Corporation (US) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016090157-A1 | BIOMOLECULE CONJUGATES | CELGENE CORPORATION (US) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10335495-B2 | Biomolecule conjugates | DNPEP, NAPA, NCL | MEN1 1263/4885KMT2A 2653/4885KDM4A 4528/4885 |
| US-20170360952-A1 | BIOMOLECULE CONJUGATES | DNPEP, NAPA, NCL | MEN1 1263/4885KMT2A 2653/4885KDM4A 4528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.