Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19582438 | 0.78 | ACKR3 (0.85) | ACKR3 | |
| SCHEMBL17801994 | 0.71 | ACKR3 (0.73) | ACKR3 | |
| SCHEMBL19582445 | 0.70 | ACKR3 (1.00) | ACKR3 | |
| SCHEMBL17801896 | 0.68 | ACKR3 (0.57) | ACKR3 | |
| SCHEMBL17801895 | 0.66 | ACKR3 (1.00) | ACKR3 | |
| SCHEMBL19582538 | 0.66 | ACKR3 (0.79) | ACKR3 | |
| SCHEMBL19582402 | 0.66 | ACKR3 (1.00) | ACKR3 | |
| SCHEMBL17801993 | 0.66 | ACKR3 (1.00) | ACKR3 | |
| SCHEMBL19582534 | 0.65 | ACKR3 (1.00) | ACKR3 | |
| SCHEMBL19582215 | 0.65 | ACKR3 (0.82) | ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227263-A1 | CXCR7 RECEPTOR MODULATORS | Actelion Pharmaceuticals Ltd (CH) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016087370-A1 | CXCR7 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2016-06-09 | — | — | WO | disclosed |