Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 3/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16332510 | 0.77 | KDM4E (0.46) | KDM4ELMNABRD4POLBMAPK1 | |
| SCHEMBL1715909 | 0.75 | CACNA1H (0.47) | KDM4ELMNABRD4MAPTKDM4A | |
| SCHEMBL31565511 | 0.73 | NAMPT (0.43) | KDM4ELMNAMAPTKDM4AGFER | |
| SCHEMBL15862073 | 0.72 | NAMPT (0.39) | KDM4ELMNAMAPTKDM4ASTK17B | |
| SCHEMBL2022140 | 0.72 | HDAC6 (0.52) | KDM4EBRD4POLBMAPTHSD17B10 | |
| SCHEMBL28842745 | 0.72 | KDM4E (0.48) | KDM4ELMNABRD4POLBMAPK1 | |
| SCHEMBL7970926 | 0.72 | DHODH (0.46) | KDM4ELMNABRD4POLBMAPK1 | |
| SCHEMBL28366489 | 0.72 | MAPT (0.70) | KDM4ELMNABRD4MAPTL3MBTL1 | |
| SCHEMBL30466612 | 0.72 | MAPT (0.70) | KDM4ELMNABRD4MAPTL3MBTL1 | |
| SCHEMBL7153464 | 0.70 | MAPT (0.49) | KDM4ELMNABRD4POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227302-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2018-07-11 | — | — | EP | disclosed |
| EP-3227302-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016087373-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | WO | disclosed |