Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 14/20 | 0.68 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26470 | 0.82 | SCD (0.70) | SCDDCTPP1 | |
| SCHEMBL1378991 | 0.81 | SCD (1.00) | SCDDCTPP1 | |
| SCHEMBL4914115 | 0.80 | SCD (0.75) | SCDDCTPP1 | |
| SCHEMBL4091944 | 0.80 | SCD (0.72) | SCD | |
| SCHEMBL13043719 | 0.80 | SCD (0.63) | SCDDCTPP1 | |
| SCHEMBL17803771 | 0.79 | SCD (0.69) | SCDDCTPP1 | |
| SCHEMBL3668407 | 0.78 | SCD (0.73) | SCDDCTPP1 | |
| SCHEMBL3666246 | 0.78 | SCD (0.77) | SCDDCTPP1 | |
| SCHEMBL1378674 | 0.78 | SCD (0.93) | SCDDCTPP1 | |
| SCHEMBL24230 | 0.77 | SCD (0.71) | SCDDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9358250-B2 | Methods of using SCD1 antagonists | GENENTECH, INC. (US) | 2016-06-07 | — | — | US | disclosed |
| US-9358250-B2 | Methods of using SCD1 antagonists | GENENTECH, INC. (US) | 2016-06-07 | — | — | US | disclosed |