SCHEMBL17809041

SCHEMBL17809041

c1ccc(-c2cc(-n3c4ccccc4c4ccc(-c5ccc6c(c5)c5ccccc5n6-c5ccc6ccccc6c5)cc43)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.39
MAPK1 P28482 3/20 0.39
HSD17B10 Q99714 2/20 0.39
TSHR P16473 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HPGD P15428 4/20 0.38
MAPK10 P53779 2/20 0.35
MAPK9 P45984 1/20 0.35
CYP1A1 P04798 1/20 0.34
CYP1B1 Q16678 1/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
ALDH1A1 P00352 3/20 0.34
NTSR1 P30989 1/20 0.34
PTGES O14684 1/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6373388 1.00 MAPT (0.39) MAPTMAPK1HSD17B10TSHRNPSR1
SCHEMBL6375273 0.92 CYP1A1 (0.39) MAPTMAPK1HSD17B10NPSR1HPGD
SCHEMBL6375679 0.92 CYP1A1 (0.39) MAPTMAPK1HSD17B10NPSR1HPGD
SCHEMBL9888895 0.92 CYP1A1 (0.39) MAPTMAPK1HSD17B10NPSR1HPGD
SCHEMBL23370438 0.92 MAPK1 (0.42) MAPTMAPK1HSD17B10TSHRNPSR1
SCHEMBL18213917 0.92 MAPT (0.36) MAPTMAPK1HSD17B10TSHRNPSR1
SCHEMBL23370452 0.91 MAPK1 (0.41) MAPTMAPK1HSD17B10TSHRNPSR1
SCHEMBL6373199 0.91 MAPT (0.41) MAPTMAPK1HSD17B10TSHRNPSR1
SCHEMBL6375067 0.90 KDM4E (0.43) MAPTMAPK1HSD17B10TSHRNPSR1
SCHEMBL6373233 0.90 KDM4E (0.43) MAPTMAPK1HSD17B10TSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9515271-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2016-12-06 US disclosed
US-9515271-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2016-12-06 US disclosed
US-20160163999-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-09 US disclosed
US-20160163999-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-09 US disclosed