SCHEMBL17809193

SCHEMBL17809193

c1ccc(-c2ccc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6cccc(-c7nc(-c8ccccc8)cc(-c8ccccc8)n7)c6)c5c43)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.41
L3MBTL1 Q9Y468 4/20 0.41
ATM Q13315 1/20 0.41
KMT2A Q03164 9/20 0.40
MEN1 O00255 8/20 0.40
ALDH1A1 P00352 7/20 0.40
MAPT P10636 6/20 0.40
HPGD P15428 6/20 0.40
LMNA P02545 2/20 0.40
NTSR1 P30989 1/20 0.39
GLA P06280 1/20 0.38
GAA P10253 1/20 0.36
DHODH Q02127 1/20 0.35
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ADORA2A P29274 2/20 0.34
ADORA1 P30542 2/20 0.34
IL1R1 P14778 1/20 0.34
HDAC4 P56524 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17809126 1.00 KDM4E (0.41) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL25966149 1.00 KDM4E (0.41) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL22596268 0.99 KDM4E (0.42) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL22596307 0.99 KDM4E (0.42) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL22595844 0.98 KDM4E (0.40) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL17809106 0.98 KDM4E (0.40) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL22596291 0.96 MEN1 (0.41) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL23370559 0.96 KMT2A (0.43) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL17809164 0.96 KMT2A (0.41) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL17809168 0.96 KMT2A (0.41) KDM4EL3MBTL1ATMKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed