SCHEMBL17809257

SCHEMBL17809257

c1ccc(-c2cc(-c3ccccc3)nc(-c3cccc(-n4c5ccccc5c5ccc6c7ccccc7n(-c7cccc8c7sc7ccccc78)c6c54)c3)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.34
MEN1 O00255 5/20 0.34
KMT2A Q03164 5/20 0.34
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.34
LMNA P02545 2/20 0.34
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TP53 P04637 1/20 0.31
GAA P10253 1/20 0.31
ALOX5 P09917 1/20 0.31
NTSR1 P30989 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17809251 0.94 TNKS (0.34) MAPTMEN1KMT2AKDM4ETNKS
SCHEMBL17809255 0.93 TNKS (0.33) MAPTMEN1KMT2AKDM4ETNKS
SCHEMBL9883288 0.93 MAPT (0.36) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL17809247 0.92 KMT2A (0.35) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL17809263 0.92 TNKS (0.33) MAPTMEN1KMT2AKDM4ETNKS
SCHEMBL17809242 0.92 KMT2A (0.35) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL17809250 0.91 MEN1 (0.34) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL17809245 0.91 TNKS (0.32) MAPTMEN1KMT2AKDM4ETNKS
SCHEMBL10014575 0.90 MEN1 (0.36) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL17809252 0.89 TNKS (0.35) MAPTKDM4ETNKSTNKS2RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed