Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.52 |
| ▸ | PIM1 | P11309 | 5/20 | 0.52 |
| ▸ | GSK3B | P49841 | 5/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
| ▸ | CDK14 | O94921 | 2/20 | 0.34 |
| ▸ | CCNY | Q8ND76 | 2/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457403 | 0.96 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3CBPIM1GSK3B | |
| Trifluoroacetic Acid SCHEMBL1781056 | 0.90 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3CBPIM1GSK3B | |
| SCHEMBL2212989 | 0.86 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CBPIM1GSK3B | |
| SCHEMBL459137 | 0.86 | PIK3CD (0.59) | PIK3CDPIK3CGPIK3CBPIM1GSK3B | |
| Trifluoroacetic Acid SCHEMBL1780544 | 0.85 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3CBPIM1GSK3B | |
| Trifluoroacetic Acid SCHEMBL1779645 | 0.85 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3CBPIM1GSK3B | |
| Formic Acid SCHEMBL15482316 | 0.84 | PIK3CD (0.51) | PIK3CDPIK3CGPIK3CBPIM1GSK3B | |
| Trifluoroacetic Acid SCHEMBL1778146 | 0.84 | PIK3CD (0.51) | PIK3CDPIK3CGPIK3CBPIM1GSK3B | |
| SCHEMBL15482317 | 0.84 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3CBPIM1GSK3B | |
| Trifluoroacetic Acid SCHEMBL1781168 | 0.83 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CBPIM1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765743-B2 | Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2014-07-01 | — | — | US | disclosed |
| US-20110118246-A1 | Novel Compounds | GLAXO GROUP LIMITED (GB) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118246-A1 | Novel Compounds | PIK3CA, PIK3C2B, PIK3CD | PIK3CD 3/4885PIK3CG 9/4885PIK3CB 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.