⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2302255 | 0.75 | — | — | |
| SCHEMBL5965648 | 0.62 | — | — | |
| SCHEMBL19996324 | 0.59 | — | — | |
| SCHEMBL10938281 | 0.59 | — | — | |
| SCHEMBL6540052 | 0.59 | — | — | |
| SCHEMBL18517971 | 0.57 | — | — | |
| SCHEMBL19286346 | 0.57 | — | — | |
| SCHEMBL380648 | 0.53 | — | — | |
| SCHEMBL23524670 | 0.53 | — | — | |
| SCHEMBL726230 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466165-B2 | 4-phenylamino-quinazolin-6-yl-amides | WARNER-LAMBERT COMPANY LLC (US) | 2013-06-18 | — | — | US | claimed |
| US-20100190977-A1 | 4-PHENYLAMINO-QUINAZOLIN-6-YL-AMIDES | PFIZER INC. | 2010-07-29 | — | — | US | claimed |
| JP-4205757-B2 | — | — | 2009-01-07 | — | — | JP | claimed |
| JP-2007536368-A | — | — | 2007-12-13 | — | — | JP | claimed |
| CN-1972688-A | 4-phenylamino-quinazolin-6-yl-amides | WARNER LAMBERT CO (US) | 2007-05-30 | — | — | CN | claimed |
| EP-1746999-A1 | 4-PHENYLAMINO-QUINAZOLIN-6-YL-AMIDES | Warner-Lambert Company LLC (US) | 2007-01-31 | — | — | EP | claimed |
| WO-2005107758-A1 | 4-PHENYLAMINO-QUINAZOLIN-6-YL-AMIDES | WARNER-LAMBERT COMPANY LLC (US) | 2005-11-17 | — | — | WO | claimed |
| US-20050250761-A1 | such as -Piperidin-1-yl-but-2-enoic acid [4(3-chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yl]-amide, used as tyrosine kinase inhibitors, for the prevention of proliferative diseases, including cancer, atherosclerosis, restenosis, endometriosis and psoriasis | PFIZER INC | 2005-11-10 | — | — | US | claimed |
| EP-0462884-B1 | TRH DERIVATIVES, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1993-06-16 | — | — | EP | claimed |
| WO-2024046471-A1 | USP1 INHIBITOR | 上海齐鲁制药研究中心有限公司 | 2024-03-07 | — | — | WO | disclosed |
| US-20230295112-A1 | HETEROAROMATIC COMPOUNDS AS VANIN INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2023-09-21 | — | — | US | disclosed |
| CN-116120285-A | Heterocyclic compound, preparation method and application thereof | 武汉人福创新药物研发中心有限公司 | 2023-05-16 | — | — | CN | disclosed |
| WO-2023078461-A1 | HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-05-11 | — | — | WO | disclosed |
| US-20230001008-A1 | COMPOSITIONS AND METHODS FOR TARGETING CELLULAR MOLECULES | KUMQUAT BIOSCIENCES INC. | 2023-01-05 | — | — | US | disclosed |
| WO-2001048138-A2 | BLEACHING COMPOSITION | UNILEVER N.V. (NL) | 2001-07-05 | — | — | WO | disclosed |
| WO-2001048137-A1 | BLEACHING COMPOSITION | UNILEVER N.V. (NL) | 2001-07-05 | — | — | WO | disclosed |
| WO-2001016261-A2 | COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE | UNILEVER PLC (GB) | 2001-03-08 | — | — | WO | disclosed |
| WO-2001016270-A1 | COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE | UNILEVER PLC (GB) | 2001-03-08 | — | — | WO | disclosed |
| WO-2001016272-A2 | LIGAND AND COMPLEX FOR CATALYTICALLY BLEACHING A SUBSTRATE | UNILEVER PLC (GB) | 2001-03-08 | — | — | WO | disclosed |
| EP-0462884-B1 | TRH DERIVATIVES, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1993-06-16 | — | — | EP | disclosed |