Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 5/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18136298 | 1.00 | DPP4 (0.34) | DPP4DPP8DPP9GLO1BACE1 | |
| SCHEMBL17813042 | 0.95 | DPP4 (0.38) | DPP4DPP8DPP9CTSCPTGS1 | |
| SCHEMBL23802494 | 0.86 | DPP4 (0.39) | DPP4DPP8DPP9GLO1BACE1 | |
| SCHEMBL16356867 | 0.86 | BACE1 (0.30) | BACE1 | |
| SCHEMBL22546322 | 0.84 | DPP4 (0.37) | DPP4DPP8DPP9GLO1BACE1 | |
| SCHEMBL18551941 | 0.82 | DPP4 (0.48) | DPP4DPP8DPP9BACE1CTSC | |
| SCHEMBL19005183 | 0.82 | DPP4 (0.48) | DPP4DPP8DPP9BACE1CTSC | |
| SCHEMBL17793245 | 0.82 | DPP4 (0.48) | DPP4DPP8DPP9BACE1CTSC | |
| SCHEMBL18214518 | 0.82 | FOLH1 (0.35) | DPP4DPP8DPP9GLO1BACE1 | |
| SCHEMBL18214552 | 0.81 | DPP4 (0.37) | DPP4DPP8DPP9GLO1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016089879-A1 | CONJUGATES OF GARFTASE INHIBITORS | ENDOCYTE, INC. (US) | 2016-06-09 | — | — | WO | disclosed |