Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.68 |
| ▸ | PRMT5 | O14744 | 17/20 | 0.67 |
| ▸ | WDR77 | Q9BQA1 | 16/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30019323 | 0.91 | CARM1 (0.74) | CARM1PRMT5WDR77LMNAHTT | |
| SCHEMBL13875133 | 0.85 | CARM1 (0.71) | CARM1PRMT5WDR77LMNAHTT | |
| SCHEMBL30124289 | 0.85 | CARM1 (0.72) | CARM1PRMT5WDR77LMNAHTT | |
| SCHEMBL28823752 | 0.85 | CARM1 (0.72) | CARM1PRMT5WDR77LMNAHTT | |
| SCHEMBL9476995 | 0.85 | CARM1 (0.67) | CARM1PRMT5WDR77LMNAHTT | |
| SCHEMBL20042490 | 0.85 | CARM1 (0.71) | CARM1PRMT5WDR77LMNAHTT | |
| SCHEMBL15823999 | 0.85 | CARM1 (0.67) | CARM1PRMT5WDR77LMNAHTT | |
| SCHEMBL29374314 | 0.85 | CARM1 (0.67) | CARM1PRMT5WDR77LMNAHTT | |
| SCHEMBL30285329 | 0.85 | CARM1 (0.67) | CARM1PRMT5WDR77LMNAHTT | |
| SCHEMBL29373628 | 0.85 | CARM1 (0.67) | CARM1PRMT5WDR77LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016089883-A1 | COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF PROSTATE CANCER | NOVARTIS AG (CH) | 2016-06-09 | — | — | WO | disclosed |