Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17808262 | 0.84 | AAK1 (0.32) | AAK1KDM4ECDK1CDK2KDR | |
| SCHEMBL17813886 | 0.81 | AAK1 (0.41) | AAK1S1PR4KDM4EGLA | |
| SCHEMBL16455750 | 0.80 | S1PR1 (0.40) | AAK1S1PR4LRRK2 | |
| SCHEMBL16455747 | 0.80 | S1PR1 (0.40) | AAK1S1PR4 | |
| SCHEMBL17813855 | 0.80 | AR (0.41) | AAK1S1PR4KDM4ELRRK2 | |
| SCHEMBL16455678 | 0.78 | AAK1 (0.39) | AAK1S1PR4KDM4ELRRK2 | |
| SCHEMBL16455748 | 0.77 | AAK1 (0.41) | AAK1S1PR4 | |
| SCHEMBL16455753 | 0.76 | SSTR4 (0.39) | AAK1KDM4ECDK1CDK2KDR | |
| SCHEMBL16455749 | 0.74 | AAK1 (0.39) | AAK1S1PR4KDM4EGLA | |
| SCHEMBL16455680 | 0.74 | CYP11B1 (0.47) | AAK1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611248-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2017-04-04 | — | — | US | disclosed |
| US-20160159767-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159767-A1 | CHEMICAL COMPOUNDS | DDT, CBR3, CYP1B1 | AAK1 1174/4885S1PR4 3327/4885KDM4E 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.