SCHEMBL1781673

SCHEMBL1781673

N[C@@H](CC1=CC(=O)C(O)=CC1=O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.44
USP2 O75604 3/20 0.43
HSD17B10 Q99714 3/20 0.43
PKM P14618 2/20 0.43
ALOX15 P16050 2/20 0.43
HIF1A Q16665 2/20 0.43
KDM4E B2RXH2 2/20 0.43
RECQL P46063 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CYP3A4 P08684 2/20 0.43
RGS12 O14924 1/20 0.43
CYP2C9 P11712 1/20 0.43
NFKB1 P19838 1/20 0.43
CASP1 P29466 1/20 0.43
BRCA1 P38398 1/20 0.43
THPO P40225 1/20 0.43
CASP7 P55210 1/20 0.43
GNAI1 P63096 1/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29280376 0.87 SLC7A5 (0.46) SLC7A5USP2HSD17B10PKMALOX15
SCHEMBL4994581 0.87 SLC7A5 (0.46) SLC7A5USP2HSD17B10PKMALOX15
SCHEMBL4308097 0.85 SLC7A5 (0.41) SLC7A5USP2HSD17B10PKMALOX15
SCHEMBL4308098 0.85 SLC7A5 (0.41) SLC7A5USP2HSD17B10PKMALOX15
SCHEMBL1076502 0.76 SLC7A5 (0.44) SLC7A5USP2HSD17B10PKMALOX15
SCHEMBL24269408 0.75 USP2 (0.43) SLC7A5USP2HSD17B10PKMALOX15
SCHEMBL22372474 0.73 SLC7A5 (0.40) SLC7A5USP2HSD17B10PKMALOX15
Benzoquinone SCHEMBL4317267 0.72 KDM4E (0.62) SLC7A5USP2HSD17B10PKMALOX15
SCHEMBL9315085 0.68 SLC7A5 (0.43) SLC7A5USP2HSD17B10PKMALOX15
SCHEMBL9315113 0.68 SLC7A5 (0.43) SLC7A5USP2HSD17B10PKMALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090291-A1 GLASS CONTAINERS AND PHARMACEUTICAL COMPOSITIONS WITH REDUCED BORON INTERACTION CORNING INCORPORATED (US) 2025-05-01 WO disclosed
US-12018265-B2 Nucleic acid encoding n-methylputrescine oxidase and uses thereof 22ND CENTURY LIMITED, LLC (US) 2024-06-25 US disclosed
US-20230029030-A1 NUCLEIC ACID ENCODING N-METHYLPUTRESCINE OXIDASE AND USES THEREOF 22ND CENTURY LIMITED, LLC (US) 2023-01-26 US disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
US-11396656-B2 Nucleic acid encoding n-methylputrescine oxidase and uses thereof 22ND CENTURY LIMITED, LLC (US) 2022-07-26 US disclosed
CN-113832119-A Improved polypeptide capable of converting substrate 3-ketodeoxynivalenol into 3-epi-deoxynivalenol 艾尔柏股份公司 2021-12-24 CN disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20200277616-A1 NUCLEIC ACID ENCODING N-METHYLPUTRESCINE OXIDASE AND USES THEREOF 22ND CENTURY LIMITED, LLC (US) 2020-09-03 US disclosed
US-10689658-B2 Nucleic acid encoding N-methylputrescine oxidase and uses thereof 22ND CENTURY LIMITED, LLC (US) 2020-06-23 US disclosed
CN-107074853-B The pyridine derived SSAO inhibitor of imidazo [4,5-c] 普罗克斯马根有限责任公司 2019-07-23 CN disclosed
US-20110250511-A1 BIOFUEL CELL SONY CORPORATION (JP) 2011-10-13 US disclosed
US-20110117453-A1 FUEL REFORMER AND POWER GENERATION APPARATUS USING THE SAME SONY CORPORATION (JP) 2011-05-19 US disclosed
US-20090210958-A1 NUCLEIC ACID ENCODING N-METHYLPUTRESCINE OXIDASE AND USES THEREOF NATIONAL RESEARCH COUNCIL OF CANADA 2009-08-20 US disclosed
EP-2038406-A2 NUCLEIC ACID ENCODING N-METHYLPUTRESCINE OXIDASE AND USES THEREOF National Research Council of Canada (CA) 2009-03-25 EP disclosed
WO-2008020333-A2 NUCLEIC ACID ENCODING N-METHYLPUTRESCINE OXIDASE AND USES THEREOF NATIONAL RESEARCH COUNCIL OF CANADA (US) 2008-02-21 WO disclosed
EP-0656791-B1 THERAPEUTIC COMPOSITIONS COMPRISING PQQ AND A REDUCING AGENT CHILDRENS MEDICAL CENTER (US) 2002-06-05 EP disclosed
EP-0656791-A4 THERAPEUTIC COMPOSITIONS AND METHODS USING PQQ. CHILDRENS MEDICAL CENTER (US) 1997-08-20 EP disclosed
US-5460819-A Method for treating PQQ-responsive heavy metal toxicity CHILDREN'S MEDICAL CENTER CORPORATION (US) 1995-10-24 US disclosed
EP-0656791-A1 THERAPEUTIC COMPOSITIONS AND METHODS USING PQQ The Children's Medical Center Corporation (US) 1995-06-14 EP disclosed
WO-1994001142-A1 THERAPEUTIC COMPOSITIONS AND METHODS USING PQQ THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1994-01-20 WO disclosed