Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.67 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15544332 | 0.90 | CNR2 (0.72) | CNR2HSD11B1NOTUMMEN1MAPT | |
| SCHEMBL15587290 | 0.84 | CNR2 (0.64) | CNR2HSD11B1NOTUMMEN1MAPT | |
| SCHEMBL15555766 | 0.83 | CNR2 (0.69) | CNR2HSD11B1NOTUMMEN1MAPT | |
| SCHEMBL15545590 | 0.81 | CNR2 (1.00) | CNR2HSD11B1NOTUMMEN1MAPT | |
| SCHEMBL15587289 | 0.78 | CNR2 (0.61) | CNR2HSD11B1NOTUMMEN1MAPT | |
| SCHEMBL15587561 | 0.75 | CNR2 (0.88) | CNR2HSD11B1NOTUMMEN1MAPT | |
| SCHEMBL15546000 | 0.73 | CNR2 (0.72) | CNR2HSD11B1MEN1KMT2A | |
| SCHEMBL15544380 | 0.72 | CNR2 (1.00) | CNR2HSD11B1NOTUM | |
| SCHEMBL15557207 | 0.71 | CNR2 (0.65) | CNR2HSD11B1MAPTNPSR1 | |
| SCHEMBL15545851 | 0.69 | CNR2 (0.71) | CNR2HSD11B1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2870139-B1 | NOVEL ADAMANTYL DERIVATIVES AS CANNABINOID RECEPTOR 2 AGONISTS | HOFFMANN LA ROCHE (CH) | 2016-06-15 | — | — | EP | claimed |