Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.71 |
| ▸ | FGFR3 | P22607 | 16/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21381506 | 0.88 | FGFR1 (0.84) | FGFR1FGFR3 | |
| Hydrochloric Acid SCHEMBL21385296 | 0.88 | FGFR1 (0.83) | FGFR1FGFR3 | |
| SCHEMBL21381583 | 0.87 | FGFR1 (0.80) | FGFR1FGFR3 | |
| SCHEMBL21381541 | 0.85 | FGFR1 (0.84) | FGFR1FGFR3 | |
| SCHEMBL15023099 | 0.83 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15023094 | 0.82 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15046130 | 0.81 | FGFR1 (1.00) | FGFR1FGFR3 | |
| Hydrochloric Acid SCHEMBL15023366 | 0.81 | FGFR1 (0.98) | FGFR1FGFR3 | |
| SCHEMBL15043290 | 0.80 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15023095 | 0.80 | FGFR1 (1.00) | FGFR1FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791140-B1 | DISUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND THEIR USE AS FGFR KINASE INHIBITORS | Bayer Pharma AG (DE) | 2016-06-15 | — | — | EP | disclosed |