SCHEMBL17818024

SCHEMBL17818024

O=C(O)OC1CCOc2cc(Oc3ccc(C(=O)Nc4ccc(-c5ccc(Cl)cc5)cn4)cc3)c(Cl)cc21

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17817985 0.93 PTGDR2 (0.58) PTGDR2
SCHEMBL17818049 0.93 PTGDR2 (0.53) PTGDR2
SCHEMBL17818096 0.92 PTGDR2 (0.52) PTGDR2
SCHEMBL17817965 0.92 PTGDR2 (0.56) PTGDR2
SCHEMBL17818028 0.91 PTGDR2 (0.62) PTGDR2
SCHEMBL17818019 0.90 PTGDR2 (0.59) PTGDR2
SCHEMBL2132344 0.89 PTGDR2 (0.75) PTGDR2
SCHEMBL17817980 0.89 PTGDR2 (0.53) PTGDR2
SCHEMBL17817974 0.88 PTGDR2 (0.63) PTGDR2
SCHEMBL17818013 0.88 PTGDR2 (0.58) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2379535-B1 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES ARRAY BIOPHARMA INC (US) 2016-06-15 EP claimed