SCHEMBL17818084

SCHEMBL17818084

COc1ccc(-c2ccc(NC(=O)c3ccc(Oc4cc5c(cc4Cl)C(OC(=O)O)CCO5)cc3)nn2)cn1

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17818096 0.93 PTGDR2 (0.52) PTGDR2
SCHEMBL17818057 0.92 PTGDR2 (0.57) PTGDR2
SCHEMBL2130145 0.90 PTGDR2 (0.64) PTGDR2
SCHEMBL17817974 0.90 PTGDR2 (0.63) PTGDR2
SCHEMBL17818020 0.90 PTGDR2 (0.66) PTGDR2
SCHEMBL17818081 0.89 PTGDR2 (0.55) PTGDR2
SCHEMBL17818011 0.88 PTGDR2 (0.57) PTGDR2
SCHEMBL17818026 0.88 PTGDR2 (0.49) PTGDR2
SCHEMBL2132870 0.88 PTGDR2 (0.55) PTGDR2
SCHEMBL17818093 0.87 PTGDR2 (0.55) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2379535-B1 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES ARRAY BIOPHARMA INC (US) 2016-06-15 EP claimed