Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.83 |
| ▸ | SMCHD1 | A6NHR9 | 1/20 | 0.69 |
| ▸ | MYO1G | B0I1T2 | 1/20 | 0.69 |
| ▸ | AIP | O00170 | 1/20 | 0.69 |
| ▸ | AP3B1 | O00203 | 1/20 | 0.69 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.69 |
| ▸ | CDC7 | O00311 | 1/20 | 0.69 |
| ▸ | SAP18 | O00422 | 1/20 | 0.69 |
| ▸ | KPNA3 | O00505 | 1/20 | 0.69 |
| ▸ | PPP6C | O00743 | 1/20 | 0.69 |
| ▸ | TCERG1 | O14776 | 1/20 | 0.69 |
| ▸ | UBE2L6 | O14933 | 1/20 | 0.69 |
| ▸ | PPP1R12A | O14974 | 1/20 | 0.69 |
| ▸ | U2SURP | O15042 | 1/20 | 0.69 |
| ▸ | SETD1A | O15047 | 1/20 | 0.69 |
| ▸ | ARPC1B | O15143 | 1/20 | 0.69 |
| ▸ | POLR1C | O15160 | 1/20 | 0.69 |
| ▸ | OGT | O15294 | 1/20 | 0.69 |
| ▸ | PPM1G | O15355 | 1/20 | 0.69 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14756416 | 0.91 | BRD4 (1.00) | BRD4SMCHD1MYO1GAIPAP3B1 | |
| SCHEMBL17451427 | 0.91 | BRD4 (1.00) | BRD4SMCHD1MYO1GAIPAP3B1 | |
| SCHEMBL1820357 | 0.91 | BRD4 (1.00) | BRD4SMCHD1MYO1GAIPAP3B1 | |
| SCHEMBL15980803 | 0.90 | BRD4 (0.86) | BRD4SMCHD1MYO1GAIPAP3B1 | |
| SCHEMBL18260657 | 0.89 | BRD4 (0.90) | BRD4SMCHD1MYO1GAIPAP3B1 | |
| SCHEMBL16906731 | 0.87 | BRD4 (0.92) | BRD4SMCHD1MYO1GAIPAP3B1 | |
| SCHEMBL26258706 | 0.87 | BRD4 (0.79) | BRD4SMCHD1MYO1GAIPAP3B1 | |
| SCHEMBL18260671 | 0.87 | BRD4 (0.85) | BRD4SMCHD1MYO1GAIPAP3B1 | |
| SCHEMBL9998885 | 0.86 | BRD4 (0.78) | BRD4SMCHD1MYO1GAIPAP3B1 | |
| SCHEMBL26258794 | 0.86 | BRD4 (0.73) | BRD4SMCHD1MYO1GAIPAP3B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2705032-B1 | DIHYDROQUINOLINE DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2016-06-15 | — | — | EP | disclosed |