SCHEMBL17822176

SCHEMBL17822176

O=C(CN1C(=O)C(=O)N(Cc2ccccc2)C1=O)c1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.81
KMT2A Q03164 3/20 0.69
RAB9A P51151 1/20 0.66
F2 P00734 1/20 0.56
PLG P00747 1/20 0.56
ELANE P08246 1/20 0.56
CTSG P08311 1/20 0.56
CMA1 P23946 1/20 0.56
CTRC Q99895 1/20 0.56
EP300 Q09472 1/20 0.55
ALDH1A1 P00352 4/20 0.54
LMNA P02545 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17833255 0.91 MAPT (0.78) MAPTKMT2ARAB9AF2PLG
SCHEMBL17833116 0.90 MAPT (0.76) MAPTKMT2ARAB9AF2PLG
SCHEMBL17835171 0.90 MAPT (0.76) MAPTKMT2ARAB9AF2PLG
SCHEMBL20276935 0.87 MAPT (0.64) MAPTKMT2ARAB9AF2PLG
SCHEMBL20277547 0.86 MAPT (0.74) MAPTKMT2ARAB9AALDH1A1LMNA
SCHEMBL17833180 0.85 MAPT (0.73) MAPTKMT2ARAB9AF2PLG
SCHEMBL8143584 0.85 KMT2A (0.76) MAPTKMT2ARAB9AF2PLG
SCHEMBL20276983 0.84 MAPT (0.68) MAPTKMT2ARAB9AF2PLG
SCHEMBL20673207 0.84 MAPT (0.71) MAPTKMT2ARAB9AALDH1A1LMNA
SCHEMBL13793073 0.82 ELANE (0.82) MAPTKMT2ARAB9AF2PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250143359-A1 COMPOUNDS THAT MODULATE GPR92 RECEPTOR ACTIVITY AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2025-05-08 US disclosed
US-20250127196-A1 COMPOUNDS THAT MODULATE FATTY ACID RECEPTOR ACTIVITY AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2025-04-24 US disclosed
EP-3229611-B1 COMPOUNDS THAT MODULATE FATTY ACID RECEPTOR ACTIVITY AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2025-03-26 EP disclosed
US-12207672-B2 Compounds that modulate GPR92 receptor activity and pet food products containing the same MARS, INCORPORATED (US) 2025-01-28 US disclosed
US-12207673-B2 Compounds that modulate fatty acid receptor activity and pet food products containing the same MARS, INCORPORATED (US) 2025-01-28 US disclosed
EP-4403042-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME Mars, Incorporated (US) 2024-07-24 EP disclosed
EP-3229612-B1 USE OF FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2024-06-26 EP disclosed
CN-117137048-A Flavor composition, food comprising the same, and method for increasing the flavor intensity of the umami taste of food 马斯公司 2023-12-01 CN disclosed
US-11185100-B2 Methods for modulating taste receptors MARS, INCORPORATED (US) 2021-11-30 US disclosed
US-11185100-B2 Methods for modulating taste receptors MARS, INCORPORATED (US) 2021-11-30 US disclosed
EP-3229612-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME Mars, Incorporated (US) 2017-10-18 EP disclosed
EP-3229606-A2 METHODS FOR MODULATING TASTE RECEPTORS Mars, Incorporated (US) 2017-10-18 EP disclosed
EP-3229610-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME Mars, Incorporated (US) 2017-10-18 EP disclosed
WO-2016094702-A2 METHODS FOR MODULATING TASTE RECEPTORS MARS, INCORPORATED (US) 2016-06-16 WO disclosed
WO-2016094702-A2 METHODS FOR MODULATING TASTE RECEPTORS MARS, INCORPORATED (US) 2016-06-16 WO disclosed
WO-2016094682-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2016-06-16 WO disclosed
WO-2016094690-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2016-06-16 WO disclosed
WO-2016094726-A2 COMPOUNDS THAT MODULATE FATTY ACID RECEPTOR ACTIVITY AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2016-06-16 WO disclosed
WO-2016094690-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2016-06-16 WO disclosed
WO-2016094682-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2016-06-16 WO disclosed