Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL10598884 | 0.99 | TSHR (0.51) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28459161 | 0.97 | TSHR (0.57) | TSHRPOLBAPEX1HTTTDP1 | |
| Acrylic Acid SCHEMBL6129067 | 0.94 | TSHR (0.52) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28333123 | 0.92 | TSHR (0.55) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10598332 | 0.92 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28631414 | 0.88 | TSHR (0.45) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28334755 | 0.88 | TSHR (0.45) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28687559 | 0.88 | TSHR (0.45) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11132856 | 0.87 | TSHR (0.41) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10973759 | 0.86 | TSHR (0.43) | TSHRPRKCAHCAR2NAAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016091937-A1 | AQUEOUS COMPOSITION COMPRISING HESPERETIN | L'OREAL (FR) | 2016-06-16 | — | — | WO | claimed |
| WO-2016091937-A1 | AQUEOUS COMPOSITION COMPRISING HESPERETIN | L'OREAL (FR) | 2016-06-16 | — | — | WO | disclosed |