SCHEMBL17825577

SCHEMBL17825577

NCC#Cc1n[nH]c2ncncc12

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AOC1 P19801 1/20 0.41
CYP2A6 P11509 5/20 0.35
CYP2E1 P05181 4/20 0.35
CYP2B6 P20813 4/20 0.35
CYP2C19 P33261 4/20 0.35
CYP1A2 P05177 3/20 0.35
CYP3A4 P08684 3/20 0.33
CYP2D6 P10635 3/20 0.33
CYP2C9 P11712 3/20 0.33
CYP2C8 P10632 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29607726 0.80 PDPK1 (0.32)
SCHEMBL4553675 0.76 KDM4E (0.34)
SCHEMBL29402652 0.76 KDM4E (0.34)
SCHEMBL887848 0.71 PIK3CD (0.36) AOC1CYP2A6CYP2E1CYP2B6CYP2C19
SCHEMBL1321549 0.69 RET (0.52) CYP3A4
SCHEMBL31001140 0.69 RET (0.52) CYP3A4
SCHEMBL3986884 0.67 RET (0.36)
SCHEMBL5705726 0.66 RET (0.35)
SCHEMBL2619222 0.66 PDPK1 (0.36) CYP1A2CYP3A4
SCHEMBL1128927 0.66 RPS6KA5 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3230467-A1 METHODS AND COMPOSITIONS FOR DETECTING ANTIBIOTIC RESISTANT BACTERIA ELITechGroup B.V. (NL) 2017-10-18 EP disclosed
WO-2016094162-A1 METHODS AND COMPOSITIONS FOR DETECTING ANTIBIOTIC RESISTANT BACTERIA ELITECHGROUP B.V. (NL) 2016-06-16 WO disclosed