Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23094097 | 0.89 | MAPT (0.47) | CYP2C19HIF1ACYP1A2CYP2D6KMT2A | |
| SCHEMBL27644513 | 0.88 | CYP1A2 (0.43) | CYP2C19HIF1ACYP1A2CYP2D6KMT2A | |
| SCHEMBL2795231 | 0.86 | MIF (0.42) | CYP2C19CYP1A2CYP2D6KMT2AMEN1 | |
| SCHEMBL17079754 | 0.84 | CYP1A2 (0.42) | CYP2C19HIF1ACYP1A2CYP2D6KMT2A | |
| SCHEMBL28660324 | 0.80 | CYP2C19 (0.53) | CYP2C19HIF1ACYP1A2CYP2D6KMT2A | |
| SCHEMBL1593582 | 0.80 | CYP2C19 (0.53) | CYP2C19HIF1AKMT2AMAPTMTNR1A | |
| SCHEMBL6647551 | 0.77 | CYP2C19 (0.56) | CYP2C19HIF1ACYP1A2CYP2D6KMT2A | |
| SCHEMBL6464415 | 0.77 | CYP2C19 (0.56) | CYP2C19HIF1ACYP1A2CYP2D6KMT2A | |
| SCHEMBL27823794 | 0.77 | CYP2C19 (0.56) | CYP2C19HIF1ACYP1A2CYP2D6KMT2A | |
| SCHEMBL8783850 | 0.77 | HIF1A (0.53) | CYP2C19HIF1ACYP1A2CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |
| CN-111138421-A | Antifungal water-soluble compound and preparation method and application thereof | 上海英诺富成生物科技有限公司 | 2020-05-12 | — | — | CN | disclosed |
| EP-3229801-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2020-04-01 | — | — | EP | disclosed |
| CN-106029672-B | serine/threonine kinase inhibitors | 基因泰克公司 | 2019-03-29 | — | — | CN | disclosed |
| US-20180030036-A1 | Factor IXa Inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-02-01 | — | — | US | disclosed |
| EP-3229801-A1 | FACTOR IXA INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2017-10-18 | — | — | EP | disclosed |
| CN-106029672-A | Serine/threonine kinase inhibitors | 基因泰克公司 | 2016-10-12 | — | — | CN | disclosed |
| WO-2016094260-A1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180030036-A1 | Factor IXa Inhibitors | F9, TFPI, F12 | CYP2C19 294/4885HIF1A 387/4885CYP1A2 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.