SCHEMBL17825909

SCHEMBL17825909

COc1ccc(CNc2ncnc3c2ncn3C2O[C@H](CO)[C@@H](O)[C@@H]2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 5/20 0.78
TP53 P04637 1/20 0.78
ADORA3 P0DMS8 1/20 0.78
TDP1 Q9NUW8 1/20 0.78
ADORA1 P30542 1/20 0.77
PRKAG1 P54619 2/20 0.73
PRKAA1 Q13131 2/20 0.73
PRKAB1 Q9Y478 2/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21139431 1.00 SLC29A1 (0.78) SLC29A1TP53ADORA3TDP1ADORA1
SCHEMBL77457 1.00 SLC29A1 (0.78) SLC29A1TP53ADORA3TDP1ADORA1
SCHEMBL13966422 1.00 SLC29A1 (0.78) SLC29A1TP53ADORA3TDP1ADORA1
SCHEMBL17371112 1.00 SLC29A1 (0.78) SLC29A1TP53ADORA3TDP1ADORA1
SCHEMBL640072 1.00 SLC29A1 (0.78) SLC29A1TP53ADORA3TDP1ADORA1
SCHEMBL17824496 1.00 SLC29A1 (0.78) SLC29A1TP53ADORA3TDP1ADORA1
SCHEMBL640071 1.00 SLC29A1 (0.78) SLC29A1TP53ADORA3TDP1ADORA1
SCHEMBL13975623 1.00 SLC29A1 (0.78) SLC29A1TP53ADORA3TDP1ADORA1
SCHEMBL25176309 0.99 SLC29A1 (0.77) SLC29A1TP53ADORA3TDP1ADORA1
SCHEMBL29697193 0.96 SLC29A1 (0.72) SLC29A1TP53ADORA3TDP1ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3229772-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF Univerzita Palackého v Olomouci (CZ) 2017-10-18 EP claimed
WO-2016091236-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2016-06-16 WO claimed
EP-3229772-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF Univerzita Palackého v Olomouci (CZ) 2017-10-18 EP disclosed
WO-2016091236-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2016-06-16 WO disclosed