Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18466738 | 1.00 | HSP90AA1 (0.46) | HSP90AA1HTTABCB1GAASMN1; SMN2 | |
| SCHEMBL18466902 | 0.98 | HSP90AA1 (0.49) | HSP90AA1HTTABCB1GAASMN1; SMN2 | |
| SCHEMBL17577105 | 0.98 | HSP90AA1 (0.49) | HSP90AA1HTTABCB1GAASMN1; SMN2 | |
| SCHEMBL18466734 | 0.95 | HSP90AA1 (0.51) | HSP90AA1HTTABCB1GAASMN1; SMN2 | |
| SCHEMBL17826505 | 0.93 | HSP90AA1 (0.55) | HSP90AA1HTTABCB1GAASMN1; SMN2 | |
| SCHEMBL18466767 | 0.89 | HTT (0.49) | HSP90AA1HTTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL17826478 | 0.89 | HTT (0.49) | HSP90AA1HTTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL17576144 | 0.88 | HSP90AA1 (0.40) | HSP90AA1HTTABCB1GAASMN1; SMN2 | |
| SCHEMBL18680425 | 0.87 | HTT (0.37) | HSP90AA1HTTABCB1GAASMN1; SMN2 | |
| SCHEMBL18679951 | 0.87 | HSP90AA1 (0.46) | HSP90AA1HTTABCB1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365676-B2 | Synthetic polymers and methods of making and using the same | BATTELLE MEMORIAL INSTITUTE (US) | 2016-06-14 | — | — | US | disclosed |