Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18466763 | 0.94 | HTT (0.42) | HTTHSP90AA1LMNAGAASMN1; SMN2 | |
| SCHEMBL18466949 | 0.94 | CYP1A2 (0.44) | HTTHSP90AA1LMNAGAASMN1; SMN2 | |
| SCHEMBL17563604 | 0.90 | HTT (0.42) | HTTHSP90AA1LMNAGAASMN1; SMN2 | |
| SCHEMBL18680200 | 0.89 | CYP1A2 (0.43) | HTTHSP90AA1LMNAGAASMN1; SMN2 | |
| SCHEMBL18062207 | 0.87 | HSP90AA1 (0.55) | HTTHSP90AA1LMNAGAASMN1; SMN2 | |
| SCHEMBL17577152 | 0.86 | HTT (0.37) | HTTHSP90AA1LMNAGAASMN1; SMN2 | |
| SCHEMBL17576144 | 0.86 | HSP90AA1 (0.40) | HTTHSP90AA1LMNAGAASMN1; SMN2 | |
| SCHEMBL18680442 | 0.85 | CYP1A2 (0.41) | HTTHSP90AA1LMNAGAASMN1; SMN2 | |
| SCHEMBL17576140 | 0.85 | HTT (0.40) | HTTHSP90AA1LMNAGAASMN1; SMN2 | |
| SCHEMBL17563719 | 0.84 | HTT (0.56) | HTTHSP90AA1LMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088671-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2017-03-30 | — | — | US | disclosed |
| US-9562137-B2 | Synthetic polymers and methods of making and using the same | BATTELLE MEMORIAL INSTITUTE (US) | 2017-02-07 | — | — | US | disclosed |
| US-20160257785-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | U.S. DEPARTMENT OF ENERGY | 2016-09-08 | — | — | US | disclosed |
| US-9365676-B2 | Synthetic polymers and methods of making and using the same | BATTELLE MEMORIAL INSTITUTE (US) | 2016-06-14 | — | — | US | disclosed |