⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663450 | 0.74 | — | — | |
| SCHEMBL12807455 | 0.69 | GAA (0.30) | — | |
| SCHEMBL14227270 | 0.67 | CRBN (0.38) | — | |
| SCHEMBL85990 | 0.67 | GAA (0.38) | — | |
| SCHEMBL2237816 | 0.67 | POLB (0.38) | — | |
| SCHEMBL243699 | 0.65 | MAPT (0.43) | — | |
| Hydrochloric Acid SCHEMBL7516042 | 0.65 | GAA (0.37) | — | |
| Ethylene SCHEMBL3939551 | 0.63 | GAA (0.36) | — | |
| Hydrochloric Acid SCHEMBL4957370 | 0.63 | MAPT (0.46) | — | |
| SCHEMBL2235681 | 0.63 | AR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2806873-B1 | AMIDINE SUBSTITUTED BETA-LACTAM COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS | AICURIS GMBH & CO KG (DE) | 2016-06-15 | — | — | EP | disclosed |