⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1627758 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28121176 | 0.97 | — | — | |
| Methyl Alcohol SCHEMBL28285301 | 0.95 | TDP1 (0.36) | — | |
| SCHEMBL28000893 | 0.85 | — | — | |
| SCHEMBL242415 | 0.85 | — | — | |
| SCHEMBL14398568 | 0.85 | — | — | |
| SCHEMBL12491696 | 0.84 | PLG (0.38) | — | |
| SCHEMBL12491694 | 0.84 | PLG (0.38) | — | |
| SCHEMBL6916964 | 0.83 | POLB (0.34) | — | |
| SCHEMBL6908462 | 0.83 | POLB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814445-B2 | Cyclic polypeptides for PCSK9 inhibition | RA PHARMACEUTICALS, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| EP-3031324-A2 | TRICYCLIC KINASE INHIBITORS | AbbVie Inc. (US) | 2016-06-15 | — | — | EP | disclosed |