Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.37 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15494112 | 1.00 | PEPD (0.45) | PEPDMEN1BLMKMT2AACE | |
| SCHEMBL23819458 | 1.00 | PEPD (0.45) | PEPDMEN1BLMKMT2AACE | |
| SCHEMBL21207444 | 1.00 | PEPD (0.45) | PEPDMEN1BLMKMT2AACE | |
| SCHEMBL14340647 | 0.95 | PEPD (0.41) | PEPDMEN1BLMKMT2A | |
| SCHEMBL12942860 | 0.95 | PEPD (0.41) | PEPDMEN1BLMKMT2A | |
| SCHEMBL15494108 | 0.95 | PEPD (0.41) | PEPDMEN1BLMKMT2A | |
| SCHEMBL3148957 | 0.86 | — | — | |
| SCHEMBL2816900 | 0.85 | PEPD (0.41) | PEPDMEN1BLMKMT2AACE | |
| SCHEMBL30922208 | 0.84 | PEPD (0.40) | PEPDMEN1BLMKMT2AACE | |
| SCHEMBL29282878 | 0.84 | PEPD (0.40) | PEPDMEN1BLMKMT2AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2506716-B1 | NOVEL TRICYCLIC COMPOUNDS | ABBVIE INC (US) | 2017-05-17 | — | — | EP | disclosed |
| EP-3031324-A2 | TRICYCLIC KINASE INHIBITORS | AbbVie Inc. (US) | 2016-06-15 | — | — | EP | disclosed |
| US-7279485-B2 | Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-10-09 | — | — | US | disclosed |