Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26802108 | 0.87 | ABCB1 (0.38) | FFAR4 | |
| SCHEMBL17827774 | 0.86 | FFAR4 (0.47) | FFAR4GRIN1GRIN2BFGFR2FGFR1 | |
| SCHEMBL17827787 | 0.83 | CHRM2 (0.35) | S1PR1 | |
| SCHEMBL9406087 | 0.83 | FFAR4 (0.45) | FFAR4GRIN1GRIN2BFGFR2FGFR1 | |
| SCHEMBL1311986 | 0.83 | FFAR4 (0.45) | FFAR4GRIN1GRIN2BFGFR2FGFR1 | |
| SCHEMBL12113639 | 0.82 | FFAR4 (0.44) | FFAR4GRIN1GRIN2BFGFR2FGFR1 | |
| SCHEMBL22277497 | 0.82 | FFAR4 (0.44) | FFAR4GRIN1GRIN2BFGFR2FGFR1 | |
| SCHEMBL22277356 | 0.82 | FFAR4 (0.44) | FFAR4GRIN1GRIN2BFGFR2FGFR1 | |
| SCHEMBL10091331 | 0.82 | FGFR2 (0.40) | FFAR4KDM4EFGFR2FGFR1PTPRC | |
| SCHEMBL21609916 | 0.81 | MPL (0.38) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9404038-B2 | Cyclopropyl-bearing liquid crystal compounds and mixtures | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-08-02 | — | — | US | disclosed |
| US-9404038-B2 | Cyclopropyl-bearing liquid crystal compounds and mixtures | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-08-02 | — | — | US | disclosed |
| US-20160168461-A1 | CYCLOPROPYL-BEARING LIQUID CRYSTAL COMPOUNDS AND MIXTURES | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-06-16 | — | — | US | disclosed |
| US-20160168461-A1 | CYCLOPROPYL-BEARING LIQUID CRYSTAL COMPOUNDS AND MIXTURES | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-06-16 | — | — | US | disclosed |