SCHEMBL17827781

SCHEMBL17827781

Fc1cc(C2CCC(C3CC3)CC2)ccc1-c1cc(F)c(C(F)(F)Oc2cc(F)c(F)c(F)c2)c(F)c1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
APP P05067 1/20 0.31
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16978419 0.97 CYP3A4 (0.34) CYP3A4CYP2C9APPPDK2
SCHEMBL17147777 0.97 CYP3A4 (0.32) CYP3A4CYP2C9APP
SCHEMBL13342144 0.95 FASN (0.36) CYP3A4CYP2C9APP
SCHEMBL12626299 0.93
SCHEMBL16978430 0.92 CYP3A4 (0.38) CYP3A4CYP2C9APPPDK2
SCHEMBL17147774 0.92 CYP3A4 (0.36) CYP3A4CYP2C9APPPDK2
SCHEMBL12626218 0.91 FASN (0.31)
SCHEMBL2741554 0.91 FASN (0.37) CYP3A4CYP2C9APPPDK2
SCHEMBL18855036 0.91 CYP3A4 (0.30) CYP3A4CYP2C9APPPDK2
SCHEMBL18854986 0.91 ALOX5AP (0.31) CYP3A4CYP2C9APPPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9404038-B2 Cyclopropyl-bearing liquid crystal compounds and mixtures SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) 2016-08-02 US disclosed
US-9404038-B2 Cyclopropyl-bearing liquid crystal compounds and mixtures SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) 2016-08-02 US disclosed
US-20160168461-A1 CYCLOPROPYL-BEARING LIQUID CRYSTAL COMPOUNDS AND MIXTURES SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) 2016-06-16 US disclosed
US-20160168461-A1 CYCLOPROPYL-BEARING LIQUID CRYSTAL COMPOUNDS AND MIXTURES SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) 2016-06-16 US disclosed