SCHEMBL1782934

SCHEMBL1782934

OCc1ccc(O)c2ncccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 1.00
L3MBTL1 Q9Y468 5/20 1.00
LMNA P02545 4/20 1.00
HTT P42858 3/20 1.00
NPC1 O15118 2/20 1.00
RAB9A P51151 2/20 1.00
GAA P10253 2/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
ALOX12 P18054 4/20 0.73
TP53 P04637 3/20 0.73
MAPT P10636 3/20 0.73
TSHR P16473 1/20 0.73
PAX8 Q06710 1/20 0.68
NPSR1 Q6W5P4 1/20 0.68
BRD4 O60885 3/20 0.62
ALDH1A1 P00352 2/20 0.62
ALOX15 P16050 2/20 0.62
NFKB1 P19838 1/20 0.62
NFKB2 Q00653 1/20 0.62
RELA Q04206 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30159468 1.00 KDM4E (1.00) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL27906143 0.98 KDM4E (0.96) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL4564667 0.98 KDM4E (0.96) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL9177673 0.89 KDM4E (0.79) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL31237495 0.89 KDM4E (0.79) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL15854518 0.87 KDM4E (0.77) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL1317977 0.87 KDM4E (0.77) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL11307415 0.86 KDM4E (0.75) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL114710 0.85 KDM4E (0.74) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL27911013 0.85 KDM4E (0.74) KDM4EL3MBTL1LMNAHTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2571951-B1 CONTROLLED CURE ALIPHATIC LAMINATING ADHESIVE USING NON-MIGRATING BLOCKING AGENTS FOR ORGANOMETALLIC CATALYSTS Henkel IP & Holding GmbH (DE) 2016-07-13 EP claimed
CN-103097484-B Controlled cure aliphatic laminating adhesives using non-migratory blockers for organometallic catalysts HENKEL CORP 2014-07-30 CN claimed
CN-103097484-A Controlled cure aliphatic laminating adhesives using non-migratory blockers for organometallic catalysts HENKEL CORP 2013-05-08 CN claimed
US-20130078473-A1 CONTROLLED CURE ALIPHATIC LAMINATING ADHESIVE USING NON-MIGRATING BLOCKING AGENTS FOR ORGANOMETALLIC CATALYSTS HENKEL CORPORATION (US) 2013-03-28 US claimed
EP-2571951-A2 CONTROLLED CURE ALIPHATIC LAMINATING ADHESIVE USING NON-MIGRATING BLOCKING AGENTS FOR ORGANOMETALLIC CATALYSTS Henkel Corporation (US) 2013-03-27 EP claimed
WO-2011146252-A2 CONTROLLED CURE ALIPHATIC LAMINATING ADHESIVE USING NON-MIGRATING BLOCKING AGENTS FOR ORGANOMETALLIC CATALYSTS HENKEL CORPORATION (US) 2011-11-24 WO claimed
US-3956420-A CPOLYOLEFIN COMPOSITION FOR ELECTRICAL INSULATIONFERROCENE, 8-SUBSTITUTED QUINOLINE DAINICHI-NIPPON CABLES, LTD. (JA) 1976-05-11 US claimed
EP-3856813-B1 USE OF POLYVINYLACETATE POLYMERS OR COPOLYMERS TO INCREASE THE VISCOSITY OF THE ISOCYANATE COMPONENT OF A TWO-COMPONENT CURABLE POLYMERIC SYSTEM HENKEL AG & CO KGAA (DE) 2024-11-06 EP disclosed
EP-4077575-B1 FOLD PROTECTION FOR SPIRAL FILTRATION MODULES UTILIZING UV CURED POLYURETHANE AND METHOD OF PROVIDING SAME HENKEL AG & CO KGAA (DE) 2024-11-06 EP disclosed
US-12043731-B2 Use of polyvinylacetate polymers or copolymers to increase the viscosity of the isocyanate component of a two-component curable polymeric system HENKEL AG & CO. KGAA (DE) 2024-07-23 US disclosed
US-20240209247-A1 GREEN ALTERNATIVE POLYURETHANE ADHESIVE HENKEL AG & CO KGAA (DE) 2024-06-27 US disclosed
CN-114761510-B Fold protection for spiral filtration modules using UV cured polyurethane and method of providing same 汉高股份有限及两合公司 2024-05-28 CN disclosed
EP-4337739-A1 GREEN ALTERNATIVE POLYURETHANE ADHESIVE Henkel AG & Co. KGaA (DE) 2024-03-20 EP disclosed
CN-1144564-A Retroreflective article and method of making the same MINNESOTA MINING & MFG (US) 1997-03-05 CN disclosed
EP-0752117-A1 RETROREFLECTIVE ARTICLE AND METHOD OF MAKING THE SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-01-08 EP disclosed
US-5474827-A Wash and wear fabric comprising an aromatic bidentate compound being chemical bonding to reflective metal and binder MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-12-12 US disclosed
WO-1995025970-A2 RETROREFLECTIVE ARTICLE AND METHOD OF MAKING THE SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-09-28 WO disclosed
US-4894219-A ADRENERGIC BLOCKING AGENTS, ANALYZING UNIVERSITY OF FLORIDA (US) 1990-01-16 US disclosed
US-4317887-A NUCLEOPHILIC-MODIFIED POLYACRYLAMIDE, POLYSTYRENE, AND DIVINYLBENZENE-STYRENE COPOLYMER; ION EXCHANGE RESINS; FIREPROOFING YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1982-03-02 US disclosed
US-3956420-A CPOLYOLEFIN COMPOSITION FOR ELECTRICAL INSULATIONFERROCENE, 8-SUBSTITUTED QUINOLINE DAINICHI-NIPPON CABLES, LTD. (JA) 1976-05-11 US disclosed