Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 5/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 4/20 | 0.42 |
| ▸ | EP300 | Q09472 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17830697 | 0.92 | APEX1 (0.51) | APEX1MEN1KMT2ACTDSP1CCR6 | |
| SCHEMBL17830698 | 0.92 | APEX1 (0.57) | APEX1MEN1KMT2ACTDSP1PTPN7 | |
| SCHEMBL17830700 | 0.90 | MEN1 (0.55) | APEX1MEN1KMT2ACTDSP1PTPN7 | |
| SCHEMBL17830705 | 0.90 | APEX1 (0.61) | APEX1MEN1KMT2ACTDSP1PTPN7 | |
| SCHEMBL17830696 | 0.89 | APEX1 (0.54) | APEX1MEN1KMT2ACTDSP1PTPN7 | |
| SCHEMBL17832352 | 0.88 | APEX1 (0.57) | APEX1MEN1KMT2ACTDSP1PTPN7 | |
| SCHEMBL17830694 | 0.87 | PTPN7 (0.56) | APEX1MEN1KMT2ACTDSP1PTPN7 | |
| SCHEMBL17830699 | 0.86 | MEN1 (0.61) | APEX1MEN1KMT2ACTDSP1PTPN7 | |
| SCHEMBL17830695 | 0.85 | KAT2B (0.54) | APEX1MEN1KMT2ACTDSP1PTPN7 | |
| SCHEMBL17830693 | 0.83 | PTPN7 (0.60) | APEX1MEN1KMT2ACTDSP1PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943506-B2 | BCL6 inhibitors as anticancer agents | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-9943506-B2 | BCL6 inhibitors as anticancer agents | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-20160166549-A1 | BCL6 INHIBITORS AS ANTICANCER AGENTS | CORNELL UNIVERSITY | 2016-06-16 | — | — | US | disclosed |
| US-20160166549-A1 | BCL6 INHIBITORS AS ANTICANCER AGENTS | CORNELL UNIVERSITY | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166549-A1 | BCL6 INHIBITORS AS ANTICANCER AGENTS | BCL6, BCL6B, BAZ2A | APEX1 3100/4885MEN1 3321/4885KMT2A 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.