Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 3/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966116 | 0.78 | BRD4 (0.44) | EPHX2NR1H2 | |
| SCHEMBL17891872 | 0.78 | BRD4 (0.44) | EPHX2NR1H2 | |
| SCHEMBL338176 | 0.78 | BRD4 (0.44) | EPHX2NR1H2 | |
| SCHEMBL27889839 | 0.77 | — | — | |
| SCHEMBL1924098 | 0.75 | EPHX2 (0.41) | EPHX2NR1H2SLC6A12SLC6A11SLC6A13 | |
| Hydrochloric Acid SCHEMBL28821979 | 0.75 | — | — | |
| SCHEMBL27980219 | 0.75 | — | — | |
| SCHEMBL337975 | 0.75 | EPHX2 (0.41) | EPHX2NR1H2SLC6A12SLC6A11SLC6A13 | |
| SCHEMBL17891868 | 0.74 | NR1H2 (0.51) | EPHX2NR1H2 | |
| SCHEMBL17891867 | 0.74 | NR1H2 (0.51) | EPHX2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016093342-A1 | DIHYDROPYRIMIDINE-2-ONE COMPOUNDS AND MEDICINAL USES THEREOF | 日本たばこ産業株式会社 | 2016-06-16 | — | — | WO | disclosed |