Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 7/20 | 0.55 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | CSK | P41240 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.44 |
| ▸ | CAMK1G | Q96NX5 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17829825 | 0.95 | CCR4 (0.54) | CCR4CACNA2D1FLT3BTKERBB4 | |
| SCHEMBL17829659 | 0.92 | CCR4 (0.46) | CCR4CACNA2D1FLT3CSKBTK | |
| SCHEMBL17829627 | 0.92 | CCR4 (0.63) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829812 | 0.91 | CCR4 (0.56) | CCR4CACNA2D1FLT3CSKBTK | |
| SCHEMBL17829852 | 0.88 | CCR4 (0.52) | CCR4CACNA2D1FLT3CSKBTK | |
| SCHEMBL17829801 | 0.87 | CCR4 (0.53) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829804 | 0.86 | CCR4 (0.64) | CCR4CACNA2D1FLT3CSKBTK | |
| SCHEMBL17829855 | 0.86 | CCR4 (0.63) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829620 | 0.85 | CCR4 (0.76) | CCR4CACNA2D1FLT3 | |
| SCHEMBL17829807 | 0.84 | CCR4 (0.72) | CCR4CACNA2D1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |