Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 14/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 14/20 | 0.56 |
| ▸ | PARP1 | P09874 | 9/20 | 0.56 |
| ▸ | PARP2 | Q9UGN5 | 6/20 | 0.55 |
| ▸ | PTGES | O14684 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833163 | 0.90 | TNKS (0.69) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL17829781 | 0.84 | TNKS (0.54) | TNKSTNKS2PARP1PARP2PTGES | |
| SCHEMBL17829769 | 0.84 | TNKS (0.60) | TNKSTNKS2PARP1PARP2PTGES | |
| SCHEMBL17829782 | 0.83 | TNKS (0.59) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL17829780 | 0.82 | TNKS (0.57) | TNKSTNKS2PARP1PARP2PTGES | |
| SCHEMBL17829754 | 0.80 | TNKS (0.69) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL17829783 | 0.79 | TNKS (0.53) | TNKSTNKS2PARP1PARP2PTGES | |
| SCHEMBL11086311 | 0.79 | TNKS (0.74) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL17830142 | 0.79 | TNKS (0.70) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL17829757 | 0.78 | TNKS (0.65) | TNKSTNKS2PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |