Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 7/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.56 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.53 |
| ▸ | RAD52 | P43351 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PRKCH | P24723 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | LATS1 | O95835 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17829568 | 0.84 | RAD52 (0.59) | RAD52KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL17829800 | 0.83 | RAD52 (0.58) | RAD52KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL17829798 | 0.82 | POLB (0.53) | RAD52KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL17829886 | 0.81 | POLB (0.55) | RAD52KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL17833229 | 0.80 | RAD52 (0.50) | RAD52KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL17829861 | 0.80 | RAD52 (0.59) | RAD52KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL17829585 | 0.79 | RAD52 (0.55) | RAD52KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL17829817 | 0.79 | RAD52 (0.55) | RAD52KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL17830139 | 0.79 | RAD52 (0.57) | RAD52KMT2AALDH1A1MAPK1POLB | |
| SCHEMBL17829819 | 0.78 | RAD52 (0.53) | RAD52KMT2AALDH1A1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |