Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.46 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.45 |
| ▸ | DTYMK | P23919 | 4/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12729458 | 1.00 | POLB (0.49) | POLBP2RY6P2RY2P2RY4ENPP1 | |
| SCHEMBL12729465 | 0.83 | POLB (0.49) | POLBP2RY6P2RY2P2RY4ENPP1 | |
| SCHEMBL17833850 | 0.83 | POLB (0.49) | POLBP2RY6P2RY2P2RY4ENPP1 | |
| SCHEMBL17833839 | 0.83 | POLB (0.46) | POLBP2RY6P2RY2P2RY4ENPP1 | |
| SCHEMBL12729405 | 0.83 | POLB (0.46) | POLBP2RY6P2RY2P2RY4ENPP1 | |
| SCHEMBL12729456 | 0.81 | POLB (0.54) | POLBP2RY6P2RY2P2RY4ENPP1 | |
| SCHEMBL12729491 | 0.80 | POLB (0.50) | POLBP2RY6P2RY2P2RY4ENPP1 | |
| SCHEMBL12729466 | 0.80 | POLB (0.52) | POLBP2RY6P2RY2P2RY4ENPP1 | |
| SCHEMBL17833848 | 0.80 | POLB (0.52) | POLBP2RY6P2RY2P2RY4ENPP1 | |
| SCHEMBL17833843 | 0.79 | POLB (0.54) | POLBP2RY6P2RY2P2RY4ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168636-A1 | NUCLEOTIDE ANALOGS | HELICOS BIOSCIENCES CORPORATION | 2016-06-16 | — | — | US | disclosed |