Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833937 | 0.74 | TSHR (0.36) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9177920 | 0.73 | MEN1 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9001590 | 0.72 | CA1 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11487053 | 0.69 | KMT2A (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15715192 | 0.68 | CA12 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20862832 | 0.68 | MEN1 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20862913 | 0.68 | FABP3 (0.40) | HTTL3MBTL1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11797004 | 0.67 | CA1 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15715691 | 0.66 | CA1 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12667894 | 0.66 | CA1 (0.42) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094489-A1 | PHOSPHORUS LIGANDS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-06-16 | — | — | WO | disclosed |