Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 15/20 | 0.86 |
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.75 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL17821378 | 0.93 | MYC (1.00) | MYCMEN1KMT2ASMN1; SMN2HPGD | |
| Trifluoroacetic Acid SCHEMBL17821379 | 0.93 | MYC (1.00) | MYCMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL17834348 | 0.88 | MYC (0.75) | MYCMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL20362861 | 0.88 | MYC (0.82) | MYCMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL17834351 | 0.87 | MEN1 (1.00) | MYCMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL17834253 | 0.87 | MEN1 (1.00) | MYCMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL17834350 | 0.87 | MEN1 (0.76) | MYCMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL17821453 | 0.87 | MYC (0.84) | MYCMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL17821454 | 0.87 | MYC (0.84) | MYCMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL17834257 | 0.86 | MEN1 (1.00) | MYCMEN1KMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094688-A1 | FUSED 1,3-AZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-06-16 | — | — | WO | disclosed |