Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 8/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17836745 | 1.00 | CHRNA7 (0.39) | CHRNA7EGFRMETROS1ALK | |
| SCHEMBL10242556 | 0.91 | EGFR (0.42) | CHRNA7EGFRMETROS1ALK | |
| SCHEMBL416614 | 0.91 | EGFR (0.42) | CHRNA7EGFRMETROS1ALK | |
| SCHEMBL416615 | 0.91 | EGFR (0.42) | CHRNA7EGFRMETROS1ALK | |
| SCHEMBL10242564 | 0.88 | CHRNA7 (0.48) | CHRNA7EGFRMETROS1ALK | |
| SCHEMBL411332 | 0.88 | EGFR (0.44) | CHRNA7EGFRMETROS1ALK | |
| SCHEMBL413915 | 0.88 | EGFR (0.44) | CHRNA7EGFRMETROS1ALK | |
| SCHEMBL10242563 | 0.88 | EGFR (0.44) | CHRNA7EGFRMETROS1ALK | |
| SCHEMBL412716 | 0.88 | CHRNA7 (0.48) | CHRNA7EGFRMETROS1ALK | |
| SCHEMBL412717 | 0.88 | CHRNA7 (0.48) | CHRNA7EGFRMETROS1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | disclosed |