Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10204785 | 0.84 | APP (0.44) | TYK2APPRORCMEN1KMT2A | |
| SCHEMBL10242565 | 0.81 | NR1I2 (0.39) | TYK2NR1I2AHRPOLBAPP | |
| SCHEMBL416341 | 0.81 | NR1I2 (0.39) | TYK2NR1I2AHRPOLBAPP | |
| SCHEMBL416340 | 0.81 | NR1I2 (0.39) | TYK2NR1I2AHRPOLBAPP | |
| SCHEMBL417607 | 0.80 | CHRNA7 (0.48) | TYK2MAPT | |
| SCHEMBL417606 | 0.80 | CHRNA7 (0.48) | TYK2MAPT | |
| SCHEMBL10242559 | 0.80 | CHRNA7 (0.48) | TYK2MAPT | |
| SCHEMBL417657 | 0.78 | CA12 (0.48) | PDE4BRORCMEN1KMT2AMAPT | |
| SCHEMBL417656 | 0.78 | CA12 (0.48) | PDE4BRORCMEN1KMT2AMAPT | |
| SCHEMBL417399 | 0.78 | CHRNA7 (0.49) | TYK2NR1I2AHRPOLBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | claimed |