Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 12/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DDX3X | O00571 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17836764 | 1.00 | CHRNA7 (0.56) | CHRNA7CA12CA1CA2CA9 | |
| SCHEMBL412329 | 0.98 | CHRNA7 (0.53) | CHRNA7CA12CA1CA2CA9 | |
| SCHEMBL412328 | 0.98 | CHRNA7 (0.53) | CHRNA7CA12CA1CA2CA9 | |
| SCHEMBL10240739 | 0.98 | CHRNA7 (0.53) | CHRNA7CA12CA1CA2CA9 | |
| SCHEMBL416677 | 0.91 | CHRNA7 (0.67) | CHRNA7CA12CA1CA2CA9 | |
| SCHEMBL418605 | 0.91 | CHRNA7 (0.67) | CHRNA7CA12CA1CA2CA9 | |
| SCHEMBL10242566 | 0.91 | CHRNA7 (0.67) | CHRNA7CA12CA1CA2CA9 | |
| SCHEMBL416437 | 0.90 | CHRNA7 (0.61) | CHRNA7CA12CA1CA2CA9 | |
| SCHEMBL17836749 | 0.90 | CHRNA7 (0.61) | CHRNA7CA12CA1CA2CA9 | |
| SCHEMBL413708 | 0.90 | CHRNA7 (0.61) | CHRNA7CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | disclosed |