SCHEMBL17839999

SCHEMBL17839999

CN1CCC[C@H]1CN(C(=O)O)c1ccccc1-c1ccc(F)c(Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 19/20 0.58
CHRNB1 P11230 1/20 0.45
CHRNB2 P17787 1/20 0.45
CHRNB4 P30926 1/20 0.45
CHRNA3 P32297 1/20 0.45
CHRNB3 Q05901 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17840065 1.00 CHRM3 (0.58) CHRM3CHRNB1CHRNB2CHRNB4CHRNA3
SCHEMBL17840147 0.91 CHRM3 (0.61) CHRM3
SCHEMBL17840145 0.91 CHRM3 (0.56) CHRM3
SCHEMBL17840143 0.91 CHRM3 (0.56) CHRM3
SCHEMBL17840176 0.91 CHRM3 (0.56) CHRM3
SCHEMBL17840175 0.91 CHRM3 (0.56) CHRM3
SCHEMBL17840038 0.90 CHRM3 (0.59) CHRM3
SCHEMBL17840036 0.90 CHRM3 (0.59) CHRM3
SCHEMBL17840001 0.89 CHRM3 (0.58) CHRM3CHRNB1CHRNB2CHRNB4CHRNA3
SCHEMBL17840003 0.89 CHRM3 (0.58) CHRM3CHRNB1CHRNB2CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688739-A1 NOVEL PYRROLIDINIUM COMPOUNDS HAVING ANTAGONISTIC ACTIVITY AGAINST MUSCARINIC RECEPTORS AND USE THEREOF eFlask Co., Ltd. (KR) 2026-02-11 EP disclosed
WO-2024205157-A1 NOVEL PYRROLIDINIUM COMPOUNDS HAVING ANTAGONISTIC ACTIVITY AGAINST MUSCARINIC RECEPTORS AND USE THEREOF EFLASK CO., LTD. (KR) 2024-10-03 WO disclosed
US-9828339-B2 Biphenyl derivatives and methods for preparing same DONG-A ST CO., LTD (KR) 2017-11-28 US disclosed
US-20160176816-A1 NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME DONG-A ST CO., LTD (KR) 2016-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160176816-A1 NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME CHRM2, CHRM3, CHRM5 CHRM3 2/4885CHRNB1 15/4885CHRNB2 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.