Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 17/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17840244 | 1.00 | CHRM3 (0.52) | CHRM3CHRM5CHRM1CHRNB2CHRNB4 | |
| SCHEMBL17840090 | 0.92 | CHRM3 (0.54) | CHRM3CHRM5CHRM1CHRNB2CHRNB4 | |
| SCHEMBL17840092 | 0.92 | CHRM3 (0.54) | CHRM3CHRM5CHRM1CHRNB2CHRNB4 | |
| SCHEMBL17840125 | 0.90 | CHRM3 (0.56) | CHRM3 | |
| SCHEMBL17840314 | 0.90 | CHRM3 (0.56) | CHRM3CHRM5CHRM1 | |
| SCHEMBL17840127 | 0.90 | CHRM3 (0.56) | CHRM3 | |
| SCHEMBL17840316 | 0.90 | CHRM3 (0.56) | CHRM3CHRM5CHRM1 | |
| SCHEMBL17840299 | 0.89 | CHRM3 (0.56) | CHRM3CHRM5CHRM1 | |
| SCHEMBL17840300 | 0.89 | CHRM3 (0.56) | CHRM3CHRM5CHRM1 | |
| SCHEMBL17797008 | 0.87 | CHRM3 (0.51) | CHRM3CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828339-B2 | Biphenyl derivatives and methods for preparing same | DONG-A ST CO., LTD (KR) | 2017-11-28 | — | — | US | disclosed |
| US-20160176816-A1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG-A ST CO., LTD (KR) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160176816-A1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | CHRM2, CHRM3, CHRM5 | CHRM3 2/4885CHRM5 3/4885CHRM1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.