Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.72 |
| ▸ | RELA | Q04206 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | STS | P08842 | 5/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9142556 | 1.00 | NPC1 (0.72) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL19188726 | 1.00 | NPC1 (0.72) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9141566 | 1.00 | NPC1 (0.72) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9455825 | 0.96 | NPC1 (0.67) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9545764 | 0.96 | NPC1 (0.67) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL19373812 | 0.95 | MAPT (0.74) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL19373809 | 0.95 | MAPT (0.74) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL10344104 | 0.95 | MAPT (0.74) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL19373815 | 0.95 | MAPT (0.74) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL19373811 | 0.95 | MAPT (0.74) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153564-B | Templated synthesis of shape controlled polymer nanofibers by Chemical Vapor Deposition (CVD) in liquid crystals | 密歇根大学董事会 | 2021-10-29 | — | — | CN | disclosed |
| US-9863923-B2 | Method of detection of volatile organic compounds using liquid crystals that form a blue phase; and device for stabilization and thickness control of liquid crystal films | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2018-01-09 | — | — | US | disclosed |
| US-20160178588-A1 | METHOD OF DETECTION OF VOLATILE ORGANIC COMPOUNDS USING LIQUID CRYSTALS THAT FORM A BLUE PHASE; AND DEVICE FOR STABILIZATION AND THICKNESS CONTROL OF LIQUID CRYSTAL FILMS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2016-06-23 | — | — | US | disclosed |