Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.74 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.68 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.68 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.68 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.68 |
| ▸ | F2 | P00734 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.66 |
| ▸ | PKM | P14618 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | ABL1 | P00519 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | IDE | P14735 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30569618 | 1.00 | FOLH1 (0.74) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL29358108 | 1.00 | FOLH1 (0.74) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL31248175 | 1.00 | FOLH1 (0.74) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL15279176 | 1.00 | FOLH1 (0.74) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL17975148 | 1.00 | FOLH1 (0.74) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL18690250 | 1.00 | FOLH1 (0.74) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL31510306 | 1.00 | FOLH1 (0.74) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL518031 | 1.00 | FOLH1 (0.74) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL13907093 | 1.00 | FOLH1 (0.74) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL30689887 | 1.00 | FOLH1 (0.74) | FOLH1PRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376169-A1 | COMPOSITIONS AND METHODS FOR TARGETED CYTOKINE DELIVERY | WASHINGTON UNIVERSITY | 2024-11-14 | — | — | US | disclosed |
| EP-4382535-A2 | COMPOSITIONS AND METHODS FOR TARGETED CYTOKINE DELIVERY | Washington University (US) | 2024-06-12 | — | — | EP | disclosed |
| EP-3875152-B1 | COMPOSITIONS AND METHODS FOR TARGETED CYTOKINE DELIVERY | WASHINGTON UNIVERSITY ST LOUIS (US) | 2024-04-10 | — | — | EP | disclosed |
| US-11938193-B2 | Compositions comprising chemerin and methods of use thereof | WASHINGTON UNIVERSITY (US) | 2024-03-26 | — | — | US | disclosed |
| US-20240092854-A1 | COMPOSITIONS AND METHODS FOR TARGETED CYTOKINE DELIVERY | WASHINGTON UNIVERSITY | 2024-03-21 | — | — | US | disclosed |
| US-20240075155-A1 | COMPOSITIONS COMPRISING CHEMERIN AND METHODS OF USE THEREOF | WASHINGTON UNIVERSITY | 2024-03-07 | — | — | US | disclosed |
| US-11897929-B2 | Compositions and methods for targeted cytokine delivery | WASHINGTON UNIVERSITY (US) | 2024-02-13 | — | — | US | disclosed |
| US-11713342-B2 | Compositions and methods for targeted cytokine delivery | WASHINGTON UNIVERSITY (US) | 2023-08-01 | — | — | US | disclosed |
| US-20210284706-A1 | COMPOSITIONS AND METHODS FOR TARGETED CYTOKINE DELIVERY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-09-16 | — | — | US | disclosed |
| EP-3875152-A1 | COMPOSITIONS AND METHODS FOR TARGETED CYTOKINE DELIVERY | Washington University (US) | 2021-09-08 | — | — | EP | disclosed |
| US-10793613-B2 | Compositions and methods for targeted cytokine delivery | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-10-06 | — | — | US | disclosed |
| US-20190119345-A1 | COMPOSITIONS AND METHODS FOR TARGETED CYTOKINE DELIVERY | WASHINGTON UNIVERSITY | 2019-04-25 | — | — | US | disclosed |
| US-20190092831-A1 | COMPOSITIONS AND METHODS FOR TARGETED CYTOKINE DELIVERY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-03-28 | — | — | US | disclosed |
| US-20190008982-A1 | COMPOSITIONS COMPRISING CHEMERIN AND METHODS OF USE THEREOF | WASHINGTON UNIVERSITY | 2019-01-10 | — | — | US | disclosed |
| EP-3411414-A2 | COMPOSITIONS AND METHODS FOR TARGETED CYTOKINE DELIVERY | Washington University (US) | 2018-12-12 | — | — | EP | disclosed |
| EP-3233192-A2 | COMPOSITIONS AND METHODS FOR TARGETED CYTOKINE DELIVERY | Washington University (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2017136818-A2 | COMPOSITIONS AND METHODS FOR TARGETED CYTOKINE DELIVERY | WASHINGTON UNIVERSITY (US) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017120589-A1 | COMPOSITIONS COMPRISING CHEMERIN AND METHODS OF USE THEREOF | WASHINGTON UNIVERSITY (US) | 2017-07-13 | — | — | WO | disclosed |
| US-20170095577-A1 | NONINVASIVE IMAGING OF FOCAL ATHEROSCLEROTIC LESIONS USING FLUORESCENCE MOLECULAR TOMOGRAPHY | WASHINGTON UNIVERSITY | 2017-04-06 | — | — | US | disclosed |
| WO-2016100375-A2 | COMPOSITIONS AND METHODS FOR TARGETED CYTOKINE DELIVERY | WASHINGTON UNIVERSITY (US) | 2016-06-23 | — | — | WO | disclosed |